TCT-292 Evaluation of Neointimal Healing and Late luminal Loss of Endothelial Progenitor Cell Capturing Sirolimus-Eluting (COMBO) Stent by Optical Coherence Tomography: the EGO-COMBO Study
نویسندگان
چکیده
منابع مشابه
Evaluation of Early Healing Profile and Neointimal Transformation Over 24 Months Using Longitudinal Sequential Optical Coherence Tomography Assessments and 3-Year Clinical Results of the New Dual-Therapy Endothelial Progenitor Cell Capturing Sirolimus-Eluting Combo Stent
Monotherapy drug-eluting stents (DES) suppress neointimal proliferation and reduce the 1-year target lesion revascularization rate better than bare-metal stents but have other issues about safety and efficacy. Inadequate endothelial strut coverage causes stent thrombosis requiring stringent dual-antiplatelet therapy. Late catch-up with cumulative increase in the target lesion revascularization ...
متن کاملDevelopment of a novel prohealing stent designed to deliver sirolimus from a biodegradable abluminal matrix.
BACKGROUND We aimed to demonstrate that, by separating endothelial progenitor cell capture from sirolimus delivery through the application of drug to the abluminal surface of the stent, the degree of endothelialization can be enhanced. METHODS AND RESULTS Stainless steel R Stents, with biodegradable SynBiosys polymer coating with sirolimus abluminally applied and surface modified with anti-CD...
متن کاملNeointimal proliferation around malapposed struts of a sirolimus-eluting stent: optical coherence tomography findings.
between baseline plaque burden and subsequent remodelling of atherosclerotic left main coronary arteries: a serial intravascular ultrasound study with long-term ( 12 months) follow-up. Eur Heart J 2006;27:1778–1784. First published on May 22, 2006, doi:10.1093/ eurheartj/ehl034. 7. Sipahi I, Tuzcu EM, Schoenhagen P, Nicholls SJ, Ozduran V, Kapadia S, Nissen SE. Compensatory enlargement of human...
متن کاملOne-year head to head comparison of the neointimal response between sirolimus eluting stent with reservoir technology and everolimus eluting stent: an optical coherence tomography study.
OBJECTIVE to compare the vascular healing process between the sirolimus-eluting NEVO and the everolimus-eluting Xience stent by optical coherence tomography (OCT) at 1-year follow-up. BACKGROUND Presence of durable polymer on a drug-eluting metallic stent may be the basis of an inflammatory reaction with abnormal healing response. The NEVO stent, having a bioresorbable polymer eluted by reser...
متن کاملNeointimal coverage of sirolimus-eluting stents at 6-month follow-up: evaluated by optical coherence tomography.
AIMS Since the intravascular ultrasound (IVUS) cannot detect neointimal layers in the majority of sirolimus-eluting stents (SES) at the chronic phase, it is still controversial to what extent SES remain uncovered. However, optical coherence tomography (OCT) with excellent resolution may be able to detect thinner neointima. METHODS AND RESULTS A total of 34 patients (57 SES) underwent OCT and ...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2012
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2012.08.316